Muscle protein recovery in post-traumatic tetraplegic patients after rehabilitation.
Source: Europa Medicophysica 33(1):9-12.
Abstract: Study of the rate of recovery for muscle protein metabolism in tetraplegic patients after rehabilitation. Involved in the study were five males 32.2 +/- 16.4 years, with post traumatic tetraplegia. Before and after rehabilitation readings were taken for 24-hour urinary excretion (CRu), 3-methylhistidine (3MHIu), along with a ratio of MHIu/CRu. Utilizing Talbot's equation (SMM=17.9x Cru) striatal muscle mass (SMM) was determined. There was a significant increase in post-rehabilitation values. CRu increased from 83.5 +/- 23.9 to 100.6 +/- 23.8 mu mol/kg/24 hours (p<0.02)3 MHIu increased for 1.25 +/- 0.42 to 2.59 +/- 0.31 mu mol/kg/24 hours (p<0.01). The ratio of MHIu/CRu increased from 0.0146 +/- 0.0023 to 0.023 +/- 0.004 mu mol/mu mol/kg (p<0.02). SMM increase was 36.5%. A significant muscle and myofibril mass recovery resulted from rehabilitation treatment for tetraplegic patients. (CIRRIE Abstract)
Institution: SFM, CMRM, 27040 Montescano(PV), Italy